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Executive Leadership

More on how this works in practice: Common questions about fractional leadership

Fractional Executive Leadership
Senior operational leadership, engaged on your terms.

Some programs need a COO or senior operations executive. Not every organization is ready — or resourced — to hire one full-time.

ABRA Clinical Consulting's Fractional Executive Leadership service places Angela Brady directly inside your clinical operations function as a senior principal accountable for the outcomes that matter most: delivery performance, governance integrity, organizational alignment, and operational scalability.

What this engagement covers

Organizational Design & Governance Architecture

Tailored to your program portfolio and regulatory obligations, building the structural foundation your clinical operations function needs to perform with consistency and accountability

Executive Decision Support

Across clinical delivery, vendor management, and cross-functional operations, providing a senior operational voice at the table when consequential decisions are being made

Accountability Structures & Oversight Models

Development of escalation frameworks, performance standards, and portfolio oversight models aligned to ICH E6(R3) standards that create visibility before problems escalate

High-Stakes Operational Initiatives

Leadership of restructurings, inspection readiness programs, model transitions, and integration projects where senior presence and operational credibility are non-negotiable

Board & Sponsor-Level Representation

Serving as a senior operational voice in sponsor, partner, or board-level conversations where clinical depth, executive presence, and organizational credibility matter

Who this is for

This service is built for growth-stage CROs navigating their first major scale-up, emerging biotech sponsors who need clinical operations depth without the full-time overhead, and site networks building the governance infrastructure to support a larger trial portfolio. It is also well-suited for organizations that have experienced leadership transition and need a steady, experienced hand while a permanent hire is identified.

Engagement model

Structured as a monthly retainer with defined scope, priority access to Angela directly, and a regular cadence of strategic check-ins. Engagements typically run three to twelve months, with the option to extend or transition as your needs evolve.

If your program needs a senior operational leader, start here.