Fractional Executive Leadership
Senior operational leadership, engaged on your terms.

Some programs need a COO or senior operations executive. Not every organization is ready — or resourced — to hire one full-time.

ABRA Clinical Consulting's Fractional Executive Leadership service places Angela Brady directly inside your clinical operations function as a senior principal accountable for the outcomes that matter most: delivery performance, governance integrity, organizational alignment, and operational scalability.

What this engagement covers:

• Organizational Design & Governance Architecture — Tailored to your program portfolio and regulatory obligations, building the structural foundation your clinical operations function needs to perform with consistency and accountability

• Executive Decision Support — Across clinical delivery, vendor management, and cross-functional operations, providing a senior operational voice at the table when consequential decisions are being made

• Accountability Structures & Oversight Models — Development of escalation frameworks, performance standards, and portfolio oversight models aligned to ICH E6(R3) standards that create visibility before problems escalate

• High-Stakes Operational Initiatives — Leadership of restructurings, inspection readiness programs, model transitions, and integration projects where senior presence and operational credibility are non-negotiable

• Board & Sponsor-Level Representation — Serving as a senior operational voice in sponsor, partner, or board-level conversations where clinical depth, executive presence, and organizational credibility matter

Who this is for:

This service is built for growth-stage CROs navigating their first major scale-up, emerging biotech sponsors who need clinical operations depth without the full-time overhead, and site networks building the governance infrastructure to support a larger trial portfolio. It is also well-suited for organizations that have experienced leadership transition and need a steady, experienced hand while a permanent hire is identified.

Engagement model:

Structured as a monthly retainer with defined scope, priority access to Angela directly, and a regular cadence of strategic check-ins. Engagements typically run three to twelve months, with the option to extend or transition as your needs evolve.

If your program needs a senior operational leader, start here.